NFL Week 1 Picks 2025: Best Bets, Spreads & Predictions
Are you ready for the season? It is approaching quickly, so it is time to place your picks for the games in NFL Week 1. I have found 3 games that have significant value for sports picks. Let’s take advantage of the NFL oddsmakers before it’s too late!
The Mike Vrabel Era Has Begun in New England
NFL Odds: Patriots -3.5 & Raiders +3.5
Best Pick: Patriots -3.5 (-110)
The Patriots have historically fared well in their week 1 matchups, recording a record of 6-4 over the past ten seasons. Last season, they upset the Cincinnati Bengals 16-10 on the road with their first new head coach.
Now they come into the season with another new coach, Mike Vrabel. Vrabel is known for having his players ready, and after a big spending offseason, the Patriots will come out firing in week 1. Take the Patriots with the 3.5 spread to start your NFL picks this year on the right foot!
Kyler Murray Comes Out Hot in Week One
NFL Odds: Cardinals -5.5 & Saints +5.5
Best Pick: Cardinals -5.5 (-110)
The Cardinals’ offense ranked 12th in points per game in 2024, while the Saints ranked 30th in total defense. Expect Kyler Murray, Trey McBride, and Marvin Harrison Jr. to eat up the poor Saints defense.
On the other side of the ball, the Saints will start rookie quarterback Tyler Shough or second-year gunslinger Spencer Rattler. Either way, I would not count on either to be effective come week 1.
The Broncos’ Top-Tier Defense Obliterates Rookie QB
NFL Odds: Broncos -7.5 & Titans +7.5
Best Pick: Broncos -7.5
The Broncos return a top 10 defense to face off against Titans rookie quarterback Cam Ward. Ward sees the best corner in the league, Patrick Surtain III, and an elite defensive line that ranked 3rd against the run last season. It could be a long game for a Titans team that was the worst in football just last year.
NFL Survivor: Best Picks in NFL Week 1?
The NFL 2025 season is nearing, and it is time to call your shot. Put your football IQ to the test in NFL Survivor.
NFL Survivor is where the smartest fans don’t just predict the season, they profit from it. With $100,000 in total prizes, including weekly prizes and a $50,000 grand prize, every pick matters.
Pick player props, moneylines, over/unders, or other picks to prove your expertise.
Don’t just predict. Prove it.
✅ Use code FFBBRAD to get $5 off your entry.
FAQs: NFL Survivor
Q: What is NFL Survivor?
It’s a 20-week football competition hosted by BullRush where participants make weekly picks to stay alive and advance. It’s not just about surviving… It’s about dominating the leaderboard.
Q: How does it work?
Each week, you start fresh with a $100,000 fantasy bankroll. You place picks using real NFL odds. If your return ranks in the top 80%, you survive and move to the next round. Fall into the bottom 20%, and you’re eliminated. It’s a clean slate every week, no carryover advantage.
Q: What’s the entry fee and prize pool?
Entry is $100, and the total prize pool is $100,000 guaranteed; paid out no matter how many players join. But you can save $5 off your entry by using the promo code FFBBRAD at checkout. Players who reach Week 20 get paid, with the top winner earning $50,000.
Q: What are the weekly prizes?
In Weeks 1–9, weekly winners get an automatic spot in the final round. From Weeks 10–19, the top 3 finishers each week earn cash prizes:
1st: $500 + final round entry
2nd: $350
3rd: $150
